MolNFT v1 · #104782 · protein
Crystal structure analysis of the membrane transporter fhac (double mutant V169T, I176N)
4QL0 · Filamentous hemagglutinin transporter protein fhac: “Crystal structure analysis of the membrane transporter fhac (double mutant V169T, I176N)”. X-ray diffraction, 1 ligand (PO4), 3 pockets (best druggability 0.64). MolNFT v1 #104782…
- PDB
- 4QL0
- Type
- protein
- Length
- 520 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Filamentous hemagglutinin transporter protein fhac
- UniProt
- P35077
- Ligands
- PO4
- Pockets
- 3 · best druggability 0.64
Structure
x-ray diffraction · 1 distinct chain · 15% helix, 53% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Filamentous hemagglutinin transporter protein fhac | protein | 520 | 15% helix, 53% strand | P35077 |
Ligands and binding sites
- PO4 · Phosphate ion · ion · chains A
- BOG · octyl beta-D-glucopyranoside · additive · 3 copies · chains A
- PGE · Triethylene glycol · additive · chains A
- PEG · Di(hydroxyethyl)ether · additive · chains A
- 1PE · Pentaethylene glycol · additive · chains A
- PG4 · Tetraethylene glycol · additive · chains A
- P6G · Hexaethylene glycol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 462 | 0.64 | 0.77 | 56 | empty |
| 2 | 589 | 0.62 | 0.74 | 77 | PGE, P6G |
| 3 | 123 | 0.40 | 0.75 | 19 | PEG, 1PE |
Compared structures
- 4QL0 · Crystal Structure Analysis of the Membrane Transporter FhaC (double mutant V169T, I176N) · the same entry in another collection · chain A against A, TM-score 1.00
- P35077 · AlphaFold monomer V2.0 prediction for filamentous hemagglutinin transporter protein fhac… · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35077
- Elsewhere: RCSB PDB 4QL0 · PDBe 4QL0 · UniProt P35077
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