MolNFT v1 · #104778 · protein
Crystal structure of the zebrafish CAVIN4A HR1 domain
4QKW · Muscle-related coiled-coil protein: “Crystal structure of the zebrafish CAVIN4A HR1 domain”. X-ray diffraction, 1 ligand (CL), 1 pocket (best druggability 0.64). MolNFT v1 #104778 on GenesisL1: 3D structure, binding sites and…
- PDB
- 4QKW
- Type
- protein
- Length
- 297 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Muscle-related coiled-coil protein
- UniProt
- A1L260
- Ligands
- CL
- Pockets
- 1 · best druggability 0.64
Structure
x-ray diffraction · 3 distinct chains · 97% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Muscle-related coiled-coil protein | protein | 101 | 96% helix, 0% strand | A1L260 |
| B | Muscle-related coiled-coil protein | protein | 99 | 96% helix, 0% strand | A1L260 |
| C | Muscle-related coiled-coil protein | protein | 97 | 98% helix, 0% strand | A1L260 |
Ligands and binding sites
- CL · Chloride ion · ion · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 87 | 0.64 | 0.90 | 16 | empty |
Interfaces
3 interfaces between chains.
- A–C · 1976 Ų buried · 13 hydrogen bonds · protein-protein
- A–B · 1926 Ų buried · 17 hydrogen bonds · protein-protein
- B–C · 1906 Ų buried · 18 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A1L260
- Elsewhere: RCSB PDB 4QKW · PDBe 4QKW · UniProt A1L260
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