MolNFT v1 · #104708 · protein

Crystal structure of D-xylose-proton symporter

4QIQ: “Crystal structure of D-xylose-proton symporter”. X-ray diffraction, 1 ligand (ZN), 4 pockets (best druggability 0.82). MolNFT v1 #104708 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4QIQ
Type: protein
Length: 439 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: D-xylose-proton symporter
UniProt: P0AGF4
Ligands: ZN
Pockets: 4 · best druggability 0.82

Structure

x-ray diffraction · 1 distinct chain · 80% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	D-xylose-proton symporter	protein	439	80% helix, 0% strand	P0AGF4

Ligands and binding sites

ZN · Zinc ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1066	0.82	0.83	95	empty
2	226	0.61	0.81	32	empty
3	74	0.46	0.82	17	empty
4	56	0.38	0.79	10	empty

Compared structures

4QIQ · Crystal structure of D-xylose-proton symporter · the same entry in another collection · chain A against A, TM-score 1.00
P0AGF4 · AlphaFold monomer V2.0 prediction for D-xylose-proton symporter (P0AGF4) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0AGF4
Elsewhere: RCSB PDB 4QIQ · PDBe 4QIQ · UniProt P0AGF4

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