MolNFT v1 · #10436 · protein
Interferon regulatory factor-2 DNA binding domain, NMR, 20 structures
1IRG: “Interferon regulatory factor-2 DNA binding domain, NMR, 20 structures”. Solution nmr, 2 pockets (best druggability 0.44). MolNFT v1 #10436 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1IRG
- Type
- protein
- Length
- 112 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Interferon regulatory factor-2
- UniProt
- P23906
- Pockets
- 2 · best druggability 0.44
Structure
solution nmr · 1 distinct chain · 29% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Interferon regulatory factor-2 | protein | 112 | 29% helix, 13% strand | P23906 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 75 | 0.44 | 0.81 | 18 | empty |
| 2 | 66 | 0.37 | 0.78 | 16 | empty |
Compared structures
- 1IRG · Interferon regulatory factor-2 DNA binding domain, NMR, 20 structures · the same entry in another collection · chain A against A, TM-score 1.00
- P23906 · AlphaFold monomer V2.0 prediction for interferon regulatory factor 2 (P23906) · a predicted model of the same protein · chain A against A, TM-score 0.70
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P23906
- Elsewhere: RCSB PDB 1IRG · PDBe 1IRG · UniProt P23906
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