MolNFT v1 · #104251 · protein
Structure of the resuscitation promoting factor interacting protein ripa mutated at E444
4Q4T · Peptidoglycan endopeptidase ripa: “Structure of the resuscitation promoting factor interacting protein ripa mutated at E444”. X-ray diffraction, 3 pockets (best druggability 0.57). MolNFT v1 #104251 on GenesisL1: 3D structure…
- PDB
- 4Q4T
- Type
- protein
- Length
- 208 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Peptidoglycan endopeptidase ripa
- EC
- 3.4.-.-
- UniProt
- O53168
- Pockets
- 3 · best druggability 0.57
Structure
x-ray diffraction · 1 distinct chain · 26% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Peptidoglycan endopeptidase ripa (EC 3.4.-.-) | protein | 208 | 26% helix, 24% strand | O53168 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 50 | 0.57 | 0.91 | 22 | GOL |
| 2 | 55 | 0.56 | 0.90 | 19 | FMT, GOL |
| 3 | 59 | 0.39 | 0.80 | 25 | empty |
Compared structures
- 4Q4T · Structure of the Resuscitation Promoting Factor Interacting protein RipA mutated at E444 · the same entry in another collection · chain A against A, TM-score 1.00
- O53168 · AlphaFold monomer V2.0 prediction for peptidoglycan endopeptidase ripa (O53168) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O53168
- Elsewhere: RCSB PDB 4Q4T · PDBe 4Q4T · UniProt O53168
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