MolNFT v1 · #103905 · protein
Crystal structure of influenza a virus matrix protein M1
4PUS · Matrix protein 1: “Crystal structure of influenza a virus matrix protein M1”. X-ray diffraction, 4 pockets (best druggability 0.64). MolNFT v1 #103905 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4PUS
- Type
- protein
- Length
- 290 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Matrix protein 1
- UniProt
- P05777
- Pockets
- 4 · best druggability 0.64
Structure
x-ray diffraction · 2 distinct chains · 67% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Matrix protein 1 | protein | 158 | 70% helix, 0% strand | P05777 |
| B | Matrix protein 1 | protein | 132 | 63% helix, 0% strand | P05777 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 339 | 0.64 | 0.79 | 39 | empty |
| 2 | 106 | 0.55 | 0.84 | 42 | empty |
| 3 | 62 | 0.30 | 0.74 | 16 | empty |
| 4 | 54 | 0.29 | 0.75 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 697 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 4PUS · Crystal Structure of Influenza A Virus Matrix Protein M1 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P05777
- Elsewhere: RCSB PDB 4PUS · PDBe 4PUS · UniProt P05777
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