MolNFT v1 · #103814 · protein
Caspase-8 specific unnatural amino acid peptides
4PRY · Caspase-3: “Caspase-8 specific unnatural amino acid peptides”. X-ray diffraction, 1 ligand (ACE). MolNFT v1 #103814 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4PRY
- Type
- protein
- Length
- 253 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Caspase-3; Ac-letd-cho
- EC
- 3.4.22.56
- UniProt
- P42574
- Ligands
- ACE
Structure
x-ray diffraction · 2 distinct chains · 27% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Caspase-3 (EC 3.4.22.56) | protein | 249 | 28% helix, 24% strand | P42574 |
| B | Ac-letd-cho | protein | 4 | 0% helix, 50% strand | — |
Ligands and binding sites
- ACE · Acetyl group · ligand · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 454 Ų buried · 16 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 covalent, 1 modified (covalent ligand, nonstandard).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P42574
- Elsewhere: RCSB PDB 4PRY · PDBe 4PRY · UniProt P42574
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