MolNFT v1 · #103700 · protein
Pfmcm N-terminal domain without DNA
4POF · Cell division control protein 21: “Pfmcm N-terminal domain without DNA”. X-ray diffraction, 1 ligand (ZN), 20 pockets (best druggability 0.67). MolNFT v1 #103700 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4POF
- Type
- protein
- Length
- 1,530 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cell division control protein 21
- UniProt
- Q8U3I4
- Ligands
- ZN
- Pockets
- 20 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 27% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F | Cell division control protein 21 | protein | 255 | 27% helix, 35% strand | Q8U3I4 |
Ligands and binding sites
- ZN · Zinc ion · metal · 6 copies · chains A, B, C, D, E, F
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
20 pockets found on a 1 Å grid, 15 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 292 | 0.67 | 0.82 | 27 | empty |
| 2 | 314 | 0.66 | 0.82 | 30 | empty |
| 3 | 300 | 0.66 | 0.81 | 29 | empty |
| 4 | 323 | 0.66 | 0.81 | 32 | empty |
| 5 | 325 | 0.65 | 0.81 | 32 | empty |
Interfaces
6 interfaces between chains.
- B–C · 859 Ų buried · 10 hydrogen bonds · protein-protein
- A–F · 856 Ų buried · 10 hydrogen bonds · protein-protein
- A–B · 847 Ų buried · 10 hydrogen bonds · protein-protein
- C–D · 839 Ų buried · 10 hydrogen bonds · protein-protein
- E–F · 832 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 4POF · PfMCM N-terminal domain without DNA · the same entry in another collection · chain C against C, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8U3I4
- Elsewhere: RCSB PDB 4POF · PDBe 4POF · UniProt Q8U3I4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.