MolNFT v1 · #103557 · protein

Crystal structure of patatin aged with diisopropylphosphorofluoridate

4PKA · Patatin-17: “Crystal structure of patatin aged with diisopropylphosphorofluoridate”. X-ray diffraction, 3 pockets (best druggability 0.56). MolNFT v1 #103557 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4PKA
Type: protein
Length: 357 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Patatin-17
EC: 3.1.1.-
UniProt: Q8LPW4
Pockets: 3 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 48% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X	Patatin-17 (EC 3.1.1.-)	protein	357	48% helix, 14% strand	Q8LPW4

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	162	0.56	0.81	27	empty
2	187	0.50	0.77	24	empty
3	53	0.26	0.73	17	empty

Modifications

Observed in the structure: 1 modified (nonstandard).

Compared structures

4PKA · Crystal structure of patatin aged with diisopropylphosphorofluoridate · the same entry in another collection · chain X against X, TM-score 1.00
Q8LPW4 · AlphaFold monomer V2.0 prediction for patatin-17 (Q8LPW4) · a predicted model of the same protein · chain X against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8LPW4
Elsewhere: RCSB PDB 4PKA · PDBe 4PKA · UniProt Q8LPW4

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