Dodecamer formed by a macrocyclic peptide derived from beta-2- microglobulin (63-69) - (ORN)YLL(PHI)YTE(ORN)KVA(MLE)AVK

Structure

x-ray diffraction · 1 distinct chain · 0% helix, 69% strand (DSSP).

Ligands and binding sites

• SO4 · Sulfate ion · ion · 8 copies · chains A, F, E, C, K, G, J
• CL · Chloride ion · ion · 2 copies · chains K, L

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

33 interfaces between chains.

• F–H · 270 Ų buried · 4 hydrogen bonds · protein-protein
• B–D · 262 Ų buried · 6 hydrogen bonds · protein-protein
• G–H · 262 Ų buried · 4 hydrogen bonds · protein-protein
• C–D · 261 Ų buried · 5 hydrogen bonds · protein-protein
• D–H · 258 Ų buried · 2 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 48 modified (nonstandard).

Compared structures

• 4P4X · Dodecamer formed by a macrocyclic peptide derived from beta-2-microglobulin (63-69)… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Elsewhere: RCSB PDB 4P4X · PDBe 4P4X