Dodecamer formed by a macrocyclic peptide derived from beta-2- microglobulin (63-69) - (ORN)YLL(PHI)YTE(ORN)KVA(MVA)AVK

Structure

x-ray diffraction · 1 distinct chain · 0% helix, 63% strand (DSSP).

Ligands and binding sites

• NA · Sodium ion · metal · chains H
• SO4 · Sulfate ion · ion · 8 copies · chains A, E, C, D, K, B, F, H, J, L
• CL · Chloride ion · ion · 6 copies · chains A, C, D, F, G, I, J, K

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

34 interfaces between chains.

• I–J · 299 Ų buried · 1 hydrogen bond · protein-protein
• D–E · 283 Ų buried · 5 hydrogen bonds · protein-protein
• E–F · 268 Ų buried · 5 hydrogen bonds · protein-protein
• A–C · 266 Ų buried · 6 hydrogen bonds · protein-protein
• A–E · 254 Ų buried · 2 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 48 modified (nonstandard, methylation).

Compared structures

• 4P4W · Dodecamer formed by a macrocyclic peptide derived from beta-2-microglobulin (63-69)… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Elsewhere: RCSB PDB 4P4W · PDBe 4P4W