MolNFT v1 · #102981 · protein

Crystal structure of the mouse SNX19 px domain with bound sulphate ion

4P2J · MKIAA0254 protein: “Crystal structure of the mouse SNX19 px domain with bound sulphate ion”. X-ray diffraction, 1 ligand (SO4), 2 pockets (best druggability 0.35). MolNFT v1 #102981 on GenesisL1: 3D structure, binding sites and…

PDB: 4P2J
Type: protein
Length: 229 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: MKIAA0254 protein
UniProt: Q80U53
Ligands: SO4
Pockets: 2 · best druggability 0.35

Structure

x-ray diffraction · 2 distinct chains · 41% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	MKIAA0254 protein	protein	117	39% helix, 32% strand	Q80U53
B	MKIAA0254 protein	protein	112	42% helix, 36% strand	Q80U53

Ligands and binding sites

SO4 · Sulfate ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	76	0.35	0.76	18	empty
2	52	0.29	0.75	9	empty

Interfaces

1 interface between chains.

A–B · 457 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

4P2J · Crystal structure of the mouse SNX19 PX domain with bound sulphate ion · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q80U53
Elsewhere: RCSB PDB 4P2J · PDBe 4P2J · UniProt Q80U53

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