MolNFT v1 · #102958 · protein
Crystal structure of the DBL3X-DBL4EPSILON double domain from the extracellular part of VAR2CSA PFEMP1 from plasmodium falciparum
4P1T · Erythrocyte membrane protein 1: “Crystal structure of the DBL3X-DBL4EPSILON double domain from the extracellular part of VAR2CSA PFEMP1 from…”. X-ray diffraction, 8 pockets (best druggability 0.75). MolNFT v1 #102958 on GenesisL1…
- PDB
- 4P1T
- Type
- protein
- Length
- 649 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Erythrocyte membrane protein 1
- UniProt
- Q6UDW7
- Pockets
- 8 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 54% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Erythrocyte membrane protein 1 | protein | 649 | 54% helix, 2% strand | Q6UDW7 |
Pockets
8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 478 | 0.75 | 0.84 | 46 | empty |
| 2 | 183 | 0.57 | 0.81 | 32 | empty |
| 3 | 312 | 0.55 | 0.75 | 35 | empty |
| 4 | 77 | 0.52 | 0.84 | 16 | empty |
| 5 | 82 | 0.41 | 0.79 | 17 | empty |
Modifications
Observed in the structure: 14 disulfide (disulfide).
Compared structures
- 4P1T · Crystal structure of the DBL3X-DBL4epsilon double domain from the extracellular part of… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6UDW7
- Elsewhere: RCSB PDB 4P1T · PDBe 4P1T · UniProt Q6UDW7
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