MolNFT v1 · #102893 · protein
Crystal structure of WD40 domain from toxoplasma gondii coronin
4OZU: “Crystal structure of WD40 domain from toxoplasma gondii coronin”. X-ray diffraction, 2 pockets (best druggability 0.86). MolNFT v1 #102893 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4OZU
- Type
- protein
- Length
- 390 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Coronin
- UniProt
- Q5Y1E7
- Pockets
- 2 · best druggability 0.86
Structure
x-ray diffraction · 1 distinct chain · 4% helix, 45% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Coronin | protein | 390 | 4% helix, 45% strand | Q5Y1E7 |
Ligands and binding sites
- TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains A
- ACT · Acetate ion · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 602 | 0.86 | 0.91 | 60 | ACT |
| 2 | 50 | 0.50 | 0.88 | 21 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 4OZU · Crystal Structure of WD40 domain from Toxoplasma gondii coronin · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5Y1E7
- Elsewhere: RCSB PDB 4OZU · PDBe 4OZU · UniProt Q5Y1E7
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