MolNFT v1 · #102809 · protein
Crystal structure of the keratin-like domain from the mads transcription factor sepallata 3
4OX0 · Developmental protein sepallata 3: “Crystal structure of the keratin-like domain from the mads transcription factor sepallata 3”. X-ray diffraction, 1 pocket (best druggability 0.35). MolNFT v1 #102809 on GenesisL1: 3D structure…
- PDB
- 4OX0
- Type
- protein
- Length
- 362 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Developmental protein sepallata 3
- UniProt
- O22456
- Pockets
- 1 · best druggability 0.35
Structure
x-ray diffraction · 4 distinct chains · 83% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Developmental protein sepallata 3 | protein | 93 | 84% helix, 0% strand | O22456 |
| B | Developmental protein sepallata 3 | protein | 95 | 81% helix, 0% strand | O22456 |
| C | Developmental protein sepallata 3 | protein | 91 | 87% helix, 0% strand | O22456 |
| D | Developmental protein sepallata 3 | protein | 83 | 82% helix, 0% strand | O22456 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 58 | 0.35 | 0.78 | 11 | empty |
Interfaces
5 interfaces between chains.
- B–C · 976 Ų buried · 5 hydrogen bonds · protein-protein
- A–D · 845 Ų buried · 3 hydrogen bonds · protein-protein
- A–B · 122 Ų buried · 0 hydrogen bonds · protein-protein
- B–D · 118 Ų buried · 3 hydrogen bonds · protein-protein
- A–C · 66 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 4OX0 · Crystal structure of the keratin-like domain from the MADS transcription factor Sepallata… · the same entry in another collection · chain D against D, TM-score 1.00
- O22456 · AlphaFold monomer V2.0 prediction for developmental protein sepallata 3 (O22456) · a predicted model of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O22456
- Elsewhere: RCSB PDB 4OX0 · PDBe 4OX0 · UniProt O22456
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