MolNFT v1 · #102655 · protein
X-ray crystal structure of a putative hydrolase from rickettsia typhi
4OSE: “X-ray crystal structure of a putative hydrolase from rickettsia typhi”. X-ray diffraction, 4 pockets (best druggability 0.74). MolNFT v1 #102655 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4OSE
- Type
- protein
- Length
- 567 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative hydrolase
- UniProt
- Q68WT4
- Pockets
- 4 · best druggability 0.74
Structure
x-ray diffraction · 2 distinct chains · 36% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative hydrolase | protein | 283 | 36% helix, 23% strand | Q68WT4 |
| B | Putative hydrolase | protein | 284 | 36% helix, 23% strand | Q68WT4 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 487 | 0.74 | 0.82 | 60 | empty |
| 2 | 454 | 0.72 | 0.81 | 55 | empty |
| 3 | 141 | 0.40 | 0.74 | 24 | empty |
| 4 | 56 | 0.31 | 0.77 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 551 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 4OSE · X-ray Crystal Structure of a Putative Hydrolase from Rickettsia typhi · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q68WT4
- Elsewhere: RCSB PDB 4OSE · PDBe 4OSE · UniProt Q68WT4
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