MolNFT v1 · #102606 · protein

Crystal structure of CYP105AS1

4OQS: “Crystal structure of CYP105AS1”. X-ray diffraction, 1 ligand (HEM), 2 pockets (best druggability 0.79). MolNFT v1 #102606 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4OQS
Type: protein
Length: 384 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: CYP105AS1
Ligands: HEM
Pockets: 2 · best druggability 0.79

Structure

x-ray diffraction · 1 distinct chain · 51% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	CYP105AS1	protein	384	51% helix, 10% strand	—

Ligands and binding sites

HEM · Protoporphyrin IX containing Fe · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	895	0.79	0.81	74	HEM
2	50	0.29	0.75	17	empty

Compared structures

4OQS · Crystal structure of CYP105AS1 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 4OQS · PDBe 4OQS

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