MolNFT v1 · #102574 · protein

Unliganded crystal structure of P domain from norovirus strain farmington hills 2004 co-crystallized with hbga type lea

4OPV · Major capsid protein: “Unliganded crystal structure of P domain from norovirus strain farmington hills 2004 co-crystallized with…”. X-ray diffraction, 5 pockets (best druggability 0.70). MolNFT v1 #102574 on GenesisL1: 3D structure…

PDB: 4OPV
Type: protein
Length: 613 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Major capsid protein
UniProt: R4I4P2
Pockets: 5 · best druggability 0.70

Structure

x-ray diffraction · 2 distinct chains · 7% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Major capsid protein	protein	307	6% helix, 35% strand	R4I4P2
B	Major capsid protein	protein	306	7% helix, 36% strand	R4I4P2

Pockets

5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	503	0.70	0.80	57	empty
2	54	0.70	0.98	21	empty
3	467	0.68	0.80	50	empty
4	140	0.57	0.83	22	empty
5	62	0.30	0.74	15	empty

Interfaces

1 interface between chains.

A–B · 1837 Å² buried · 18 hydrogen bonds · protein-protein

Compared structures

4OPV · Unliganded crystal structure of P domain from norovirus strain Farmington Hills 2004… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt R4I4P2
Elsewhere: RCSB PDB 4OPV · PDBe 4OPV · UniProt R4I4P2

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