MolNFT v1 · #102538 · protein
Crystal structure of P domain from norovirus strain farmington hills 2004
4OOV · Major capsid protein: “Crystal structure of P domain from norovirus strain farmington hills 2004”. X-ray diffraction, 3 pockets (best druggability 0.70). MolNFT v1 #102538 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 4OOV
- Type
- protein
- Length
- 614 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Major capsid protein
- UniProt
- R4I4P2
- Pockets
- 3 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 5% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Major capsid protein | protein | 307 | 5% helix, 35% strand | R4I4P2 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · 8 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 429 | 0.70 | 0.81 | 51 | empty |
| 2 | 450 | 0.67 | 0.79 | 49 | empty |
| 3 | 182 | 0.66 | 0.86 | 32 | EDO |
Interfaces
1 interface between chains.
- A–B · 1784 Ų buried · 19 hydrogen bonds · protein-protein
Compared structures
- 4OOV · Crystal structure of P domain from norovirus strain Farmington Hills 2004 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt R4I4P2
- Elsewhere: RCSB PDB 4OOV · PDBe 4OOV · UniProt R4I4P2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.