MolNFT v1 · #102535 · protein

Crystal structure of P domain from norovirus strain NSW0514

4OOS · VP1: “Crystal structure of P domain from norovirus strain NSW0514”. X-ray diffraction, 2 pockets (best druggability 0.53). MolNFT v1 #102535 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4OOS
Type: protein
Length: 309 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: VP1
UniProt: K4LM89
Pockets: 2 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	VP1	protein	309	6% helix, 35% strand	K4LM89

Ligands and binding sites

EDO · 1,2-ethanediol · additive · 6 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	139	0.53	0.81	22	empty
2	67	0.34	0.76	21	EDO

Compared structures

4OOS · Crystal structure of P domain from norovirus strain NSW0514 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt K4LM89
Elsewhere: RCSB PDB 4OOS · PDBe 4OOS · UniProt K4LM89

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