MolNFT v1 · #10250 · DNA
DNA bending by an adenine-thymine tract and its role in gene regulation.
1ILC · 5'-D(*AP*CP*CP*GP*AP*AP*TP*TP*CP*GP*GP*T)-3': “DNA bending by an adenine-thymine tract and its role in gene regulation.”. X-ray diffraction, 2 pockets (best druggability 0.34). MolNFT v1 #10250 on GenesisL1: 3D structure, binding…
- PDB
- 1ILC
- Type
- DNA
- Length
- 72 nucleotides
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 5'-D(*AP*CP*CP*GP*AP*AP*TP*TP*CP*GP*GP*T)-3'
- Pockets
- 2 · best druggability 0.34
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F | 5'-D(*AP*CP*CP*GP*AP*AP*TP*TP*CP*GP*GP*T)-3' | dna | 12 | — | — |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 110 | 0.34 | 0.73 | 17 | empty |
| 2 | 96 | 0.30 | 0.72 | 13 | empty |
Interfaces
4 interfaces between chains.
- E–F · 551 Ų buried · 62 hydrogen bonds · nucleic-nucleic
- A–B · 541 Ų buried · 54 hydrogen bonds · nucleic-nucleic
- C–D · 538 Ų buried · 54 hydrogen bonds · nucleic-nucleic
- A–C · 18 Ų buried · 0 hydrogen bonds · nucleic-nucleic
Compared structures
- 1ILC · DNA Bending by an Adenine-Thymine Tract and Its Role in Gene Regulation. · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1ILC · PDBe 1ILC
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