MolNFT v1 · #102257 · protein

Crystal structure of human dj-1 with glyoxylate as substrate analog

4OGF · Protein dj-1: “Crystal structure of human dj-1 with glyoxylate as substrate analog”. X-ray diffraction, 1 pocket (best druggability 0.37). MolNFT v1 #102257 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4OGF
Type: protein
Length: 187 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein dj-1
EC: 4.2.1.130
UniProt: Q99497
Pockets: 1 · best druggability 0.37

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein dj-1 (EC 4.2.1.130)	protein	187	42% helix, 21% strand	Q99497

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	58	0.37	0.79	12	empty

Modifications

Observed in the structure: 1 modified (nonstandard).

Compared structures

4OGF · Crystal Structure of Human DJ-1 with glyoxylate as substrate analog · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q99497
Elsewhere: RCSB PDB 4OGF · PDBe 4OGF · UniProt Q99497

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