MolNFT v1 · #102241 · protein
Crystal structure of a putative cystathionine beta-synthase from coxiella burnetii
4OFX: “Crystal structure of a putative cystathionine beta-synthase from coxiella burnetii”. X-ray diffraction, 1 ligand (NA), 2 pockets (best druggability 0.75). MolNFT v1 #102241 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 4OFX
- Type
- protein
- Length
- 288 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cystathionine beta-synthase
- EC
- 4.2.1.22
- UniProt
- Q83A84
- Ligands
- NA
- Pockets
- 2 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cystathionine beta-synthase (EC 4.2.1.22) | protein | 288 | 43% helix, 19% strand | Q83A84 |
Ligands and binding sites
- NA · Sodium ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 438 | 0.75 | 0.84 | 57 | empty |
| 2 | 81 | 0.34 | 0.75 | 14 | empty |
Compared structures
- 4OFX · Crystal Structure of a Putative Cystathionine beta-Synthase from Coxiella burnetii · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q83A84
- Elsewhere: RCSB PDB 4OFX · PDBe 4OFX · UniProt Q83A84
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