MolNFT v1 · #102210 · protein

Crystal structure of toxin from staphylococcus aureus MU50

4OF1 · MRNA interferase mazf: “Crystal structure of toxin from staphylococcus aureus MU50”. X-ray diffraction, 2 pockets (best druggability 0.37). MolNFT v1 #102210 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4OF1
Type: protein
Length: 230 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: MRNA interferase mazf
EC: 3.1.-.-
UniProt: Q7A2N3
Pockets: 2 · best druggability 0.37

Structure

x-ray diffraction · 1 distinct chain · 23% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	MRNA interferase mazf (EC 3.1.-.-)	protein	115	23% helix, 37% strand	Q7A2N3

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	109	0.37	0.74	23	empty
2	87	0.34	0.74	21	empty

Interfaces

1 interface between chains.

A–B · 1320 Å² buried · 31 hydrogen bonds · protein-protein

Compared structures

4OF1 · crystal structure of toxin from staphylococcus aureus Mu50 · the same entry in another collection · chain A against A, TM-score 1.00
Q7A2N3 · AlphaFold monomer V2.0 prediction for endoribonuclease mazf (Q7A2N3) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7A2N3
Elsewhere: RCSB PDB 4OF1 · PDBe 4OF1 · UniProt Q7A2N3

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