MolNFT v1 · #102193 · protein

Structure of membrane binding protein pleurotolysin B from pleurotus ostreatus

4OEJ: “Structure of membrane binding protein pleurotolysin B from pleurotus ostreatus”. X-ray diffraction, 1 ligand (CL), 5 pockets (best druggability 0.72). MolNFT v1 #102193 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4OEJ
Type: protein
Length: 464 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pleurotolysin B
UniProt: Q5W9E8
Ligands: CL
Pockets: 5 · best druggability 0.72

Structure

x-ray diffraction · 1 distinct chain · 24% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Pleurotolysin B	protein	464	24% helix, 31% strand	Q5W9E8

Ligands and binding sites

CL · Chloride ion · ion · chains A
ACT · Acetate ion · additive · 4 copies · chains A
GOL · Glycerol · additive · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	784	0.72	0.77	56	GOL
2	406	0.71	0.82	50	ACT
3	146	0.46	0.77	21	ACT
4	110	0.41	0.76	29	ACT
5	79	0.35	0.75	22	empty

Compared structures

4OEJ · Structure of membrane binding protein pleurotolysin B from Pleurotus ostreatus · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5W9E8
Elsewhere: RCSB PDB 4OEJ · PDBe 4OEJ · UniProt Q5W9E8

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