MolNFT v1 · #102117 · protein
Cryatal structure of arnb K188A complexted with plp and udp-ARA4N
4OCA · Udp-4-amino-4-deoxy-L-arabinose--oxoglutarate…: “Cryatal structure of arnb K188A complexted with plp and udp-ARA4N”. X-ray diffraction, 1 ligand (2QR), 3 pockets (best druggability 0.59). MolNFT v1 #102117 on GenesisL1: 3D…
- PDB
- 4OCA
- Type
- protein
- Length
- 363 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Udp-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase
- EC
- 2.6.1.87
- UniProt
- F5ZUF5
- Ligands
- 2QR
- Pockets
- 3 · best druggability 0.59
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Udp-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase (EC 2.6.1.87) | protein | 363 | 42% helix, 17% strand | F5ZUF5 |
Ligands and binding sites
- 2QR · (2R,3R,4S,5S)-3,4-dihydroxy-5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]tetrahydro-2H-pyr an-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 140 | 0.59 | 0.84 | 23 | 2QR |
| 2 | 65 | 0.47 | 0.83 | 20 | empty |
| 3 | 85 | 0.34 | 0.75 | 16 | empty |
Compared structures
- 4OCA · Cryatal structure of ArnB K188A complexted with PLP and UDP-Ara4N · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt F5ZUF5
- Elsewhere: RCSB PDB 4OCA · PDBe 4OCA · UniProt F5ZUF5
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.