MolNFT v1 · #102045 · protein

Crystal structure of TCDB2-TCCC3

4O9X · TCDB2, TCCC3: “Crystal structure of TCDB2-TCCC3”. X-ray diffraction, 1 ligand (HG), 20 pockets (best druggability 0.83). MolNFT v1 #102045 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4O9X
Type: protein
Length: 2,082 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: TCDB2, TCCC3
UniProt: Q8GF99, Q8GF97
Ligands: HG
Pockets: 20 · best druggability 0.83

Structure

x-ray diffraction · 1 distinct chain · 8% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	TCDB2, TCCC3	protein	2082	8% helix, 43% strand	Q8GF99, Q8GF97

Ligands and binding sites

HG · Mercury (II) ion · metal · 9 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

20 pockets found on a 1 Å grid, 15 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1171	0.83	0.84	139	HG
2	104	0.77	0.97	23	empty
3	459	0.70	0.81	57	empty
4	646	0.70	0.78	77	HG
5	311	0.69	0.83	31	HG

Compared structures

4O9X · Crystal Structure of TcdB2-TccC3 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8GF99
Every structure of UniProt Q8GF97
Elsewhere: RCSB PDB 4O9X · PDBe 4O9X · UniProt Q8GF99 · UniProt Q8GF97

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