MolNFT v1 · #101937 · protein
Structural and functional studies the characterization of C58G/C70G mutant in CYS4 zinc-finger motif in the recombination mediator protein recr
4O6P · Recombination protein recr: “Structural and functional studies the characterization of C58G/C70G mutant in CYS4 zinc-finger motif in the…”. X-ray diffraction, 1 ligand (ZN), 4 pockets (best druggability 0.57). MolNFT v1 #101937 on…
- PDB
- 4O6P
- Type
- protein
- Length
- 393 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Recombination protein recr
- UniProt
- Q8RDI4
- Ligands
- ZN
- Pockets
- 4 · best druggability 0.57
Structure
x-ray diffraction · 2 distinct chains · 39% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Recombination protein recr | protein | 197 | 42% helix, 16% strand | Q8RDI4 |
| C | Recombination protein recr | protein | 196 | 36% helix, 11% strand | Q8RDI4 |
Ligands and binding sites
- ZN · Zinc ion · metal · 2 copies · chains B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 61 | 0.57 | 0.89 | 16 | empty |
| 2 | 130 | 0.54 | 0.82 | 21 | empty |
| 3 | 69 | 0.49 | 0.84 | 22 | ZN |
| 4 | 60 | 0.47 | 0.84 | 21 | ZN |
Interfaces
1 interface between chains.
- B–C · 2110 Ų buried · 27 hydrogen bonds · protein-protein
Compared structures
- 4O6P · Structural and functional studies the characterization of C58G/C70G mutant in Cys4… · the same entry in another collection · chain B against B, TM-score 1.00
- Q8RDI4 · AlphaFold monomer V2.0 prediction for recombination protein recr (Q8RDI4) · a predicted model of the same protein · chain C against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8RDI4
- Elsewhere: RCSB PDB 4O6P · PDBe 4O6P · UniProt Q8RDI4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.