MolNFT v1 · #101589 · protein
Crystal structure of a DUF4822 family protein (EF0375) from enterococcus faecalis V583 at 1.85 a resolution
4NW4 · Lipoprotein S-layer protein: “Crystal structure of a DUF4822 family protein (EF0375) from enterococcus faecalis V583 at 1.85 a resolution”. X-ray diffraction, 3 ligands (UNL, SO4, CL), 4 pockets (best druggability 0.54). MolNFT v1…
- PDB
- 4NW4
- Type
- protein
- Length
- 273 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lipoprotein S-layer protein
- UniProt
- Q838R0
- Ligands
- UNL, SO4, CL
- Pockets
- 4 · best druggability 0.54
Structure
x-ray diffraction · 1 distinct chain · 11% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Lipoprotein S-layer protein | protein | 273 | 11% helix, 48% strand | Q838R0 |
Ligands and binding sites
- UNL · Unknown ligand · ligand · chains A
- SO4 · Sulfate ion · ion · 5 copies · chains A
- CL · Chloride ion · ion · 4 copies · chains A
- GOL · Glycerol · additive · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 134 | 0.54 | 0.81 | 23 | UNL, SO4 |
| 2 | 193 | 0.51 | 0.77 | 28 | GOL |
| 3 | 108 | 0.49 | 0.81 | 22 | SO4 |
| 4 | 83 | 0.34 | 0.74 | 19 | GOL, CL |
Modifications
Observed in the structure: 1 modified (engineered).
Compared structures
- 4NW4 · Crystal structure of a DUF4822 family protein (EF0375) from Enterococcus faecalis V583 at… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q838R0
- Elsewhere: RCSB PDB 4NW4 · PDBe 4NW4 · UniProt Q838R0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.