MolNFT v1 · #101411 · protein

Crystal structure of hepn domain protein

4NQF · Nucleotidyltransferase: “Crystal structure of hepn domain protein”. X-ray diffraction, 1 pocket (best druggability 0.45). MolNFT v1 #101411 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4NQF
Type: protein
Length: 296 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nucleotidyltransferase
UniProt: Q7CW19
Pockets: 1 · best druggability 0.45

Structure

x-ray diffraction · 2 distinct chains · 74% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nucleotidyltransferase	protein	145	75% helix, 0% strand	Q7CW19
B	Nucleotidyltransferase	protein	151	73% helix, 0% strand	Q7CW19

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	107	0.45	0.79	19	empty

Interfaces

1 interface between chains.

A–B · 254 Å² buried · 2 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 modified (engineered).

Compared structures

4NQF · Crystal structure of HEPN domain protein · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7CW19
Elsewhere: RCSB PDB 4NQF · PDBe 4NQF · UniProt Q7CW19

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.