MolNFT v1 · #101363 · protein
Structure of the nine-bladed beta-propeller of EIF3B
4NOX · Eukaryotic translation initiation factor 3 subunit B: “Structure of the nine-bladed beta-propeller of EIF3B”. X-ray diffraction, 1 ligand (CL), 2 pockets (best druggability 0.55). MolNFT v1 #101363 on GenesisL1: 3D structure…
- PDB
- 4NOX
- Type
- protein
- Length
- 460 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Eukaryotic translation initiation factor 3 subunit B
- UniProt
- G0RXS6
- Ligands
- CL
- Pockets
- 2 · best druggability 0.55
Structure
x-ray diffraction · 1 distinct chain · 2% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Eukaryotic translation initiation factor 3 subunit B | protein | 460 | 2% helix, 48% strand | G0RXS6 |
Ligands and binding sites
- CL · Chloride ion · ion · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 479 | 0.55 | 0.72 | 56 | empty |
| 2 | 104 | 0.39 | 0.75 | 18 | empty |
Compared structures
- 4NOX · Structure of the nine-bladed beta-propeller of eIF3b · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G0RXS6
- Elsewhere: RCSB PDB 4NOX · PDBe 4NOX · UniProt G0RXS6
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