MolNFT v1 · #101354 · protein
Crystal structure of the mature form of asparaginyl endopeptidase (AEP)/LEGUMAIN activated at pH 3.5
4NOJ: “Crystal structure of the mature form of asparaginyl endopeptidase (AEP)/LEGUMAIN activated at pH 3.5”. X-ray diffraction, 1 pocket (best druggability 0.34). MolNFT v1 #101354 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 4NOJ
- Type
- protein
- Length
- 260 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Legumain
- EC
- 3.4.22.34
- UniProt
- O89017
- Pockets
- 1 · best druggability 0.34
Structure
x-ray diffraction · 1 distinct chain · 31% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Legumain (EC 3.4.22.34) | protein | 260 | 31% helix, 20% strand | O89017 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 60 | 0.34 | 0.77 | 13 | empty |
Compared structures
- 4NOJ · Crystal structure of the mature form of asparaginyl endopeptidase (AEP)/Legumain… · the same entry in another collection · chain A against A, TM-score 1.00
- O89017 · AlphaFold monomer V2.0 prediction for legumain (O89017) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O89017
- Elsewhere: RCSB PDB 4NOJ · PDBe 4NOJ · UniProt O89017
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