MolNFT v1 · #101320 · protein
Structural basis for targeting the ribosomal protein S1 of mycobacterium tuberculosis by pyrazinamide
4NNK · 30S ribosomal protein S1: “Structural basis for targeting the ribosomal protein S1 of mycobacterium tuberculosis by pyrazinamide”. X-ray diffraction, 2 pockets (best druggability 0.32). MolNFT v1 #101320 on GenesisL1: 3D structure…
- PDB
- 4NNK
- Type
- protein
- Length
- 159 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 30S ribosomal protein S1
- UniProt
- P9WH43
- Pockets
- 2 · best druggability 0.32
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 30S ribosomal protein S1 | protein | 159 | 35% helix, 28% strand | P9WH43 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 79 | 0.32 | 0.74 | 17 | empty |
| 2 | 56 | 0.28 | 0.74 | 17 | empty |
Compared structures
- 4NNK · Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by… · the same entry in another collection · chain A against A, TM-score 1.00
- P9WH43 · AlphaFold monomer V2.0 prediction for 30S ribosomal protein S1 (P9WH43) · a predicted model of the same protein · chain A against A, TM-score 0.64
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P9WH43
- Elsewhere: RCSB PDB 4NNK · PDBe 4NNK · UniProt P9WH43
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