MolNFT v1 · #10129 · protein

Bovine cyclophilin 40, monoclinic form

1IHG: “Bovine cyclophilin 40, monoclinic form”. X-ray diffraction, 1 pocket (best druggability 0.54). MolNFT v1 #10129 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1IHG
Type: protein
Length: 364 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cyclophilin 40
EC: 5.2.1.8
UniProt: P26882
Pockets: 1 · best druggability 0.54

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cyclophilin 40 (EC 5.2.1.8)	protein	364	42% helix, 18% strand	P26882

Ligands and binding sites

GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	184	0.54	0.79	29	empty

Compared structures

1IHG · Bovine Cyclophilin 40, monoclinic form · the same entry in another collection · chain A against A, TM-score 1.00
P26882 · AlphaFold monomer V2.0 prediction for peptidyl-prolyl cis-trans isomerase D (P26882) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P26882
Elsewhere: RCSB PDB 1IHG · PDBe 1IHG · UniProt P26882

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