MolNFT v1 · #100980 · protein

Crystal structure of a computational designed engrailed homeodomain variant fused with YFP

4NDJ · Green fluorescent protein, chimeric CONSTRUCT,GFP-like…: “Crystal structure of a computational designed engrailed homeodomain variant fused with YFP”. X-ray diffraction, 1 ligand (CR2), 1 pocket (best druggability 0.56). MolNFT v1…

PDB: 4NDJ
Type: protein
Length: 279 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Green fluorescent protein, chimeric CONSTRUCT,GFP-like fluorescent chromoprotein FP506…
UniProt: U6GSR1
Ligands: CR2
Pockets: 1 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 27% helix, 42% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Green fluorescent protein, chimeric CONSTRUCT,GFP-like fluorescent chromoprotein FP506, related	protein	279	27% helix, 42% strand	U6GSR1

Ligands and binding sites

CR2 · {(4Z)-2-(aminomethyl)-4-[(4-hydroxyphenyl)methylidene]-5-oxo-4,5-dihydro-1H-imidazol-1-yl}acetic acid · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	69	0.56	0.88	16	empty

Modifications

Observed in the structure: 2 cofactor (chromophore).

Compared structures

4NDJ · Crystal Structure of a computational designed engrailed homeodomain variant fused with YFP · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt U6GSR1
Elsewhere: RCSB PDB 4NDJ · PDBe 4NDJ · UniProt U6GSR1

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