MolNFT v1 · #100927 · protein
Crystal structure of tcda-A2 bound to A26.8 vhh
4NC0 · Cell wall-binding repeat protein: “Crystal structure of tcda-A2 bound to A26.8 vhh”. X-ray diffraction, 1 pocket (best druggability 0.32). MolNFT v1 #100927 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4NC0
- Type
- protein
- Length
- 367 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cell wall-binding repeat protein; A26.8 vhh
- UniProt
- D5RWT1
- Pockets
- 1 · best druggability 0.32
Structure
x-ray diffraction · 2 distinct chains · 3% helix, 47% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cell wall-binding repeat protein | protein | 243 | 0% helix, 49% strand | D5RWT1 |
| B | A26.8 vhh | protein | 124 | 9% helix, 45% strand | — |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 79 | 0.32 | 0.74 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 588 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 4NC0 · Crystal Structure of TcdA-A2 Bound to A26.8 VHH · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D5RWT1
- Elsewhere: RCSB PDB 4NC0 · PDBe 4NC0 · UniProt D5RWT1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.