MolNFT v1 · #100836 · protein

Crystal structure of transcription regulation protein crp

4N9H · Catabolite gene activator: “Crystal structure of transcription regulation protein crp”. X-ray diffraction, 2 pockets (best druggability 0.77). MolNFT v1 #100836 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4N9H
Type: protein
Length: 402 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Catabolite gene activator
UniProt: C3SQJ7
Pockets: 2 · best druggability 0.77

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Catabolite gene activator	protein	201	38% helix, 31% strand	C3SQJ7

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	760	0.77	0.81	76	empty
2	510	0.72	0.81	52	empty

Interfaces

1 interface between chains.

A–B · 1920 Å² buried · 12 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 12 modified (engineered).

Compared structures

4N9H · Crystal structure of Transcription regulation Protein CRP · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt C3SQJ7
Elsewhere: RCSB PDB 4N9H · PDBe 4N9H · UniProt C3SQJ7

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