MolNFT v1 · #100470 · protein

Crystal structure of trypanosoma cruzi formiminoglutamase (oxidized) at pH 4.6

4MYL: “Crystal structure of trypanosoma cruzi formiminoglutamase (oxidized) at pH 4.6”. X-ray diffraction, 1 pocket (best druggability 0.50). MolNFT v1 #100470 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4MYL
Type: protein
Length: 288 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Formiminoglutamase
EC: 3.5.3.8
UniProt: Q4DSA0
Pockets: 1 · best druggability 0.50

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Formiminoglutamase (EC 3.5.3.8)	protein	288	43% helix, 20% strand	Q4DSA0

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	62	0.50	0.86	21	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

4MYL · Crystal structure of Trypanosoma cruzi Formiminoglutamase (oxidized) at pH 4.6 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4DSA0
Elsewhere: RCSB PDB 4MYL · PDBe 4MYL · UniProt Q4DSA0

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