MolNFT v1 · #100340 · protein
Crystal structure of mitochondrial 5'(3')-deoxy ribonucleotidase alternative spliced variant
4MUM · Mitochondrial 5' nucleotidase: “Crystal structure of mitochondrial 5'(3')-deoxy ribonucleotidase alternative spliced variant”. X-ray diffraction, 3 ligands (MG, PO4, CL), 2 pockets (best druggability 0.71). MolNFT v1 #100340 on…
- PDB
- 4MUM
- Type
- protein
- Length
- 198 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mitochondrial 5' nucleotidase
- EC
- 3.1.3.-
- UniProt
- Q2I378
- Ligands
- MG, PO4, CL
- Pockets
- 2 · best druggability 0.71
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mitochondrial 5' nucleotidase (EC 3.1.3.-) | protein | 198 | 35% helix, 15% strand | Q2I378 |
Ligands and binding sites
- MG · Magnesium ion · metal · chains A
- PO4 · Phosphate ion · ion · chains A
- CL · Chloride ion · ion · chains A
- GOL · Glycerol · additive · 8 copies · chains A
- PEG · Di(hydroxyethyl)ether · additive · 2 copies · chains A
- PG4 · Tetraethylene glycol · additive · chains A
- TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 275 | 0.71 | 0.85 | 34 | PO4, GOL, TRS |
| 2 | 55 | 0.27 | 0.73 | 17 | GOL |
Compared structures
- 4MUM · Crystal structure of mitochondrial 5'(3')-deoxy ribonucleotidase alternative spliced… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q2I378
- Elsewhere: RCSB PDB 4MUM · PDBe 4MUM · UniProt Q2I378
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.