MolNFT v1 · #100206 · protein
Crystal structure of antigen 85C-C209S mutant
4MQL · Diacylglycerol ACYLTRANSFERASE/MYCOLYLTRANSFERASE AG85C: “Crystal structure of antigen 85C-C209S mutant”. X-ray diffraction, 2 pockets (best druggability 0.34). MolNFT v1 #100206 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 4MQL
- Type
- protein
- Length
- 282 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Diacylglycerol ACYLTRANSFERASE/MYCOLYLTRANSFERASE AG85C
- EC
- 2.3.1.122, 2.3.1.20
- UniProt
- P0A4V4
- Pockets
- 2 · best druggability 0.34
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Diacylglycerol ACYLTRANSFERASE/MYCOLYLTRANSFERASE AG85C (EC 2.3.1.122, 2.3.1.20) | protein | 282 | 37% helix, 16% strand | P0A4V4 |
Ligands and binding sites
- BTB · 2-[bis-(2-hydroxy-ethyl)-amino]-2-hydroxymethyl-propane-1,3-diol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 54 | 0.34 | 0.79 | 18 | empty |
| 2 | 59 | 0.30 | 0.75 | 15 | empty |
Compared structures
- 4MQL · Crystal structure of Antigen 85C-C209S mutant · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A4V4
- Elsewhere: RCSB PDB 4MQL · PDBe 4MQL · UniProt P0A4V4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.