MolNFT v1 · #100106 · protein

Crystal structure of GH18 chitinase (G77W/E119Q mutant) from cycas revoluta in complex with (GLCNAC)4

4MNM · Chitinase a: “Crystal structure of GH18 chitinase (G77W/E119Q mutant) from cycas revoluta in complex with (GLCNAC)4”. X-ray diffraction, 2 ligands (NAG, SO4), 2 pockets (best druggability 0.56). MolNFT v1 #100106 on GenesisL1: 3D…

PDB: 4MNM
Type: protein
Length: 344 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chitinase a
EC: 3.2.1.14
UniProt: Q4W6L6
Ligands: NAG, SO4
Pockets: 2 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Chitinase a (EC 3.2.1.14)	protein	344	38% helix, 26% strand	Q4W6L6

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
SO4 · Sulfate ion · ion · 4 copies · chains A
EDO · 1,2-ethanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	258	0.56	0.76	34	NAG
2	67	0.29	0.73	17	SO4

Compared structures

4MNM · Crystal Structure of GH18 Chitinase (G77W/E119Q mutant) from Cycas revoluta in complex… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4W6L6
Elsewhere: RCSB PDB 4MNM · PDBe 4MNM · UniProt Q4W6L6

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