MolNFT v1 · #100066 · protein
Crystal structure of yafq mutant H87Q from E.COLI
4MMG · MRNA interferase yafq: “Crystal structure of yafq mutant H87Q from E.COLI”. X-ray diffraction, 1 ligand (SO4), 2 pockets (best druggability 0.45). MolNFT v1 #100066 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4MMG
- Type
- protein
- Length
- 181 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- MRNA interferase yafq
- EC
- 3.1.-.-
- UniProt
- Q47149
- Ligands
- SO4
- Pockets
- 2 · best druggability 0.45
Structure
x-ray diffraction · 2 distinct chains · 39% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | MRNA interferase yafq (EC 3.1.-.-) | protein | 91 | 38% helix, 30% strand | Q47149 |
| B | MRNA interferase yafq (EC 3.1.-.-) | protein | 90 | 39% helix, 28% strand | Q47149 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 6 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 200 | 0.45 | 0.73 | 24 | empty |
| 2 | 51 | 0.34 | 0.78 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 470 Ų buried · 12 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q47149
- Elsewhere: RCSB PDB 4MMG · PDBe 4MMG · UniProt Q47149
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