MolNFT v1 · #95551 · protein

AlphaFold monomer V2.0 prediction for gator complex protein DEPDC5 (P61460)

P61460: “AlphaFold monomer V2.0 prediction for gator complex protein DEPDC5 (P61460)”. 18 pockets (best druggability 0.87). MolNFT v1 #95551 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P61460
Type: protein
Length: 1,591 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xf81d28bD872368aF456B77A1daFfa99d2d49F26C
Molecule: Gator complex protein DEPDC5
UniProt: P61460
Pockets: 18 · best druggability 0.87

Structure

1 distinct chain · 21% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Gator complex protein DEPDC5	protein	1591	21% helix, 17% strand	P61460

Pockets

18 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1080	0.87	0.88	149	empty
2	1045	0.81	0.82	92	empty
3	648	0.75	0.81	60	empty
4	490	0.71	0.81	47	empty
5	631	0.69	0.78	66	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P61460
Elsewhere: UniProt P61460 · AlphaFold DB P61460

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