MolNFT v1 · #5640 · protein
AlphaFold monomer V2.0 prediction for isocitrate dehydrogenase KINASE/PHOSPHATASE (B7NFV2)
B7NFV2: “AlphaFold monomer V2.0 prediction for isocitrate dehydrogenase KINASE/PHOSPHATASE (B7NFV2)”. 9 pockets (best druggability 0.77). MolNFT v1 #5640 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- B7NFV2
- Type
- protein
- Length
- 578 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xcB5bE02DE6f6b8b4584C0AE7f5F86A35Bea2e97B
- Molecule
- Isocitrate dehydrogenase KINASE/PHOSPHATASE
- UniProt
- B7NFV2
- Pockets
- 9 · best druggability 0.77
Structure
1 distinct chain · 49% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Isocitrate dehydrogenase KINASE/PHOSPHATASE | protein | 578 | 49% helix, 17% strand | B7NFV2 |
Pockets
9 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 458 | 0.77 | 0.85 | 54 | empty |
| 2 | 179 | 0.76 | 0.92 | 32 | empty |
| 3 | 87 | 0.74 | 0.97 | 24 | empty |
| 4 | 123 | 0.60 | 0.85 | 28 | empty |
| 5 | 311 | 0.55 | 0.76 | 33 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B7NFV2
- Elsewhere: UniProt B7NFV2 · AlphaFold DB B7NFV2
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