MolNFT v1 · #541957 · protein

AlphaFold monomer V2.0 prediction for tight junction protein zo-2 (Q9Z0U1)

Q9Z0U1: “AlphaFold monomer V2.0 prediction for tight junction protein zo-2 (Q9Z0U1)”. 7 pockets (best druggability 0.67). MolNFT v1 #541957 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q9Z0U1
Type: protein
Length: 1,167 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x738c1929c69B751bD0Be0B962D9bac20B631aAc6
Molecule: Tight junction protein zo-2
UniProt: Q9Z0U1
Pockets: 7 · best druggability 0.67

Structure

1 distinct chain · 20% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tight junction protein zo-2	protein	1167	20% helix, 15% strand	Q9Z0U1

Pockets

7 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	441	0.67	0.79	41	empty
2	420	0.65	0.78	40	empty
3	308	0.62	0.79	33	empty
4	306	0.60	0.79	28	empty
5	371	0.59	0.76	30	empty

Compared structures

2CSJ · Solution structure of N-terminal PDZ domain from mouse TJP2 · an experimental structure of the same protein · chain A against A, TM-score 0.09
2CSJ · Solution structure of N-terminal PDZ domain from mouse TJP2 · an experimental structure of the same protein · chain A against A, TM-score 0.09

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Z0U1
Elsewhere: UniProt Q9Z0U1 · AlphaFold DB Q9Z0U1

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.