MolNFT v1 · #541715 · protein
AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase ZNRF3 (Q4KLR8)
Q4KLR8: “AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase ZNRF3 (Q4KLR8)”. 4 pockets (best druggability 0.58). MolNFT v1 #541715 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q4KLR8
- Type
- protein
- Length
- 784 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xB35df660264f41795De49C83276C108A4ba91ADE
- Molecule
- E3 ubiquitin-protein ligase ZNRF3
- UniProt
- Q4KLR8
- Pockets
- 4 · best druggability 0.58
Structure
1 distinct chain · 13% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | E3 ubiquitin-protein ligase ZNRF3 | protein | 784 | 13% helix, 9% strand | Q4KLR8 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 288 | 0.58 | 0.77 | 26 | empty |
| 2 | 54 | 0.37 | 0.80 | 13 | empty |
| 3 | 121 | 0.36 | 0.72 | 16 | empty |
| 4 | 62 | 0.35 | 0.77 | 14 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q4KLR8
- Elsewhere: UniProt Q4KLR8 · AlphaFold DB Q4KLR8
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