GL1X · GenesisL1 explorer

MolNFT v1 · #541361 · protein

AlphaFold monomer V2.0 prediction for zinc finger protein 622 (Q969S3)

Q969S3: “AlphaFold monomer V2.0 prediction for zinc finger protein 622 (Q969S3)”. 2 pockets (best druggability 0.34). MolNFT v1 #541361 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q969S3
Type
protein
Length
477 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x79a905d858Ce72991FD6E7a9C6498620f42E146D
Molecule
Zinc finger protein 622
UniProt
Q969S3
Pockets
2 · best druggability 0.34

Structure

1 distinct chain · 46% helix, 5% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AZinc finger protein 622protein47746% helix, 5% strandQ969S3

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11040.340.7314empty
2830.320.7414empty

Compared structures

  • 6LSR · Cryo-EM structure of a pre-60S ribosomal subunit - state B · an experimental structure of the same protein · chain A against 0, TM-score 0.28
  • 6LQM · Cryo-EM structure of a pre-60S ribosomal subunit - state C · an experimental structure of the same protein · chain A against 0, TM-score 0.09
  • 9GMO · eIF6-bound pre-60S large ribosomal subunit incorporating mutant uL16 · an experimental structure of the same protein · chain A against 0, TM-score 0.09

Analyse

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