MolNFT v1 · #541174 · protein

AlphaFold monomer V2.0 prediction for zinc finger protein 462 (Q96JM2)

Q96JM2: “AlphaFold monomer V2.0 prediction for zinc finger protein 462 (Q96JM2)”. 20 pockets (best druggability 0.71). MolNFT v1 #541174 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q96JM2
Type: protein
Length: 2,506 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x6Ed09D80e98fE15DE51C9E7a8896AbF1f2365C3e
Molecule: Zinc finger protein 462
UniProt: Q96JM2
Pockets: 20 · best druggability 0.71

Structure

1 distinct chain · 22% helix, 8% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Zinc finger protein 462	protein	2506	22% helix, 8% strand	Q96JM2

Pockets

20 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	376	0.71	0.83	33	empty
2	317	0.57	0.76	26	empty
3	125	0.50	0.80	19	empty
4	222	0.50	0.75	25	empty
5	224	0.46	0.74	28	empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

1X6F · Solution structures of the C2H2 type zinc finger domain of human Zinc finger protein 462 · an experimental structure of the same protein · chain A against A, TM-score 0.02
1X6F · Solution structures of the C2H2 type zinc finger domain of human zinc finger protein 462 · an experimental structure of the same protein · chain A against A, TM-score 0.02

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q96JM2
Elsewhere: UniProt Q96JM2 · AlphaFold DB Q96JM2

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