MolNFT v1 · #541170 · protein

AlphaFold monomer V2.0 prediction for E3 sumo-protein ligase ZNF451 (Q8C0P7)

Q8C0P7: “AlphaFold monomer V2.0 prediction for E3 sumo-protein ligase ZNF451 (Q8C0P7)”. 5 pockets (best druggability 0.70). MolNFT v1 #541170 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q8C0P7
Type: protein
Length: 1,056 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xf87a97E0A4bB354D834857B14296240B167cbe70
Molecule: E3 sumo-protein ligase ZNF451
UniProt: Q8C0P7
Pockets: 5 · best druggability 0.70

Structure

1 distinct chain · 32% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	E3 sumo-protein ligase ZNF451	protein	1056	32% helix, 13% strand	Q8C0P7

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	972	0.70	0.75	88	empty
2	226	0.52	0.76	34	empty
3	92	0.38	0.76	20	empty
4	76	0.33	0.75	19	empty
5	60	0.27	0.73	13	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8C0P7
Elsewhere: UniProt Q8C0P7 · AlphaFold DB Q8C0P7

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