MolNFT v1 · #541169 · protein

AlphaFold monomer V2.0 prediction for E3 sumo-protein ligase ZNF451 (Q9Y4E5)

Q9Y4E5: “AlphaFold monomer V2.0 prediction for E3 sumo-protein ligase ZNF451 (Q9Y4E5)”. 7 pockets (best druggability 0.51). MolNFT v1 #541169 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q9Y4E5
Type: protein
Length: 1,061 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x9188600a0FCa2914254C94299b1bd9721Bc4D500
Molecule: E3 sumo-protein ligase ZNF451
UniProt: Q9Y4E5
Pockets: 7 · best druggability 0.51

Structure

1 distinct chain · 32% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	E3 sumo-protein ligase ZNF451	protein	1061	32% helix, 13% strand	Q9Y4E5

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	233	0.51	0.75	35	empty
2	284	0.50	0.74	33	empty
3	271	0.49	0.73	29	empty
4	241	0.47	0.73	28	empty
5	134	0.38	0.74	25	empty

Compared structures

5D2M · Complex between human SUMO2-RANGAP1, UBC9 and ZNF451 · an experimental structure of the same protein · chain A against G, TM-score 0.01

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Y4E5
Elsewhere: UniProt Q9Y4E5 · AlphaFold DB Q9Y4E5

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